Genomic profiling of diffuse gastric carcinoma (DGC)
نویسندگان
چکیده
منابع مشابه
Genomic profiling of sinonasal squamous cell carcinoma.
BACKGROUND Sinonasal squamous cell carcinomas (SCCs) are rare tumors with no etiologic link to tobacco and alcohol, as opposed to other SCCs of the head and neck (HNSCC). Little is known about the genetic changes in sinonasal SCC. METHODS DNA copy number changes of sinonasal SCC were analyzed by multiplex ligation-dependent probe amplification (MLPA) and microarray comparative genomic hybridi...
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متن کامل[Colonic metastasis of diffuse signet ring cells gastric carcinoma].
The gastric cancer, despite its remarkable decline in incidence (1), still remains as one of the leading causes of death around the world (2) (7.2 to 20 deaths per 10 inhabitants per year) (3). The diffuse type (according to Lauren’s classification) with signet ring cells occasional presence, is less frequent but with worse prognosis than the intestinal, both commonly spread out via haematic an...
متن کاملGenomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung.
PURPOSE Although large-cell neuroendocrine carcinoma (LCNEC) of the lung shares many clinical characteristics with small-cell lung cancer (SCLC), little is known about its molecular features. We analyzed lung LCNECs to identify biologically relevant genomic alterations. EXPERIMENTAL DESIGN We performed targeted capture sequencing of all the coding exons of 244 cancer-related genes on 78 LCNEC...
متن کاملGenomic Profiling of Submucosal-Invasive Gastric Cancer by Array-Based Comparative Genomic Hybridization
Genomic copy number aberrations (CNAs) in gastric cancer have already been extensively characterized by array comparative genomic hybridization (array CGH) analysis. However, involvement of genomic CNAs in the process of submucosal invasion and lymph node metastasis in early gastric cancer is still poorly understood. In this study, to address this issue, we collected a total of 59 tumor samples...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2019
ISSN: 0923-7534
DOI: 10.1093/annonc/mdz154.005